STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
murEUDP-N-acetylmuramoyl-L-alanyl-D-glutamate-2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (438 aa)    
Predicted Functional Partners:
KKT00814.1
UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D- alanine ligase.
 
0.980
KKS99222.1
UDP-N-acetylmuramate-L-alanine ligase.
 
 0.977
KKS99219.1
UDP-N-acetylmuramoylalanine-D-glutamate ligase.
 
 0.976
KKS99221.1
UDP-N-acetylmuramate-L-alanine ligase.
  
 
 0.921
KKS99220.1
Hypothetical protein.
       0.776
KKT00115.1
Hypothetical protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
 
 
 0.703
murB
UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
  
 
 0.686
murI
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
    
 0.681
KKS99217.1
AAA ATPase central domain protein.
       0.675
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.612
Your Current Organism:
Nomurabacteria bacterium GW2011GWA24315
NCBI taxonomy Id: 1618738
Other names: C. Nomurabacteria bacterium GW2011_GWA2_43_15, Candidatus Nomurabacteria bacterium GW2011_GWA2_43_15, Parcubacteria (Nomurabacteria) bacterium GW2011_GWA2_43_15
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