node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KKS46921.1 | KKS46956.1 | UV12_C0015G0015 | UV12_C0014G0002 | Multi-sensor hybrid histidine kinase. | Polymerase protein. | 0.916 |
KKS46921.1 | KKS48085.1 | UV12_C0015G0015 | UV12_C0003G0044 | Multi-sensor hybrid histidine kinase. | Hypothetical protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.753 |
KKS46921.1 | def | UV12_C0015G0015 | UV12_C0006G0036 | Multi-sensor hybrid histidine kinase. | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 0.479 |
KKS46921.1 | nnrD | UV12_C0015G0015 | UV12_C0010G0020 | Multi-sensor hybrid histidine kinase. | ADP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. | 0.700 |
KKS46921.1 | thyA | UV12_C0015G0015 | UV12_C0010G0004 | Multi-sensor hybrid histidine kinase. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.473 |
KKS46956.1 | KKS46921.1 | UV12_C0014G0002 | UV12_C0015G0015 | Polymerase protein. | Multi-sensor hybrid histidine kinase. | 0.916 |
KKS46956.1 | KKS47611.1 | UV12_C0014G0002 | UV12_C0006G0035 | Polymerase protein. | Methionyl-tRNA formyltransferase. | 0.712 |
KKS46956.1 | KKS48085.1 | UV12_C0014G0002 | UV12_C0003G0044 | Polymerase protein. | Hypothetical protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.837 |
KKS46956.1 | def | UV12_C0014G0002 | UV12_C0006G0036 | Polymerase protein. | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 0.599 |
KKS46956.1 | nnrD | UV12_C0014G0002 | UV12_C0010G0020 | Polymerase protein. | ADP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. | 0.416 |
KKS46956.1 | thyA | UV12_C0014G0002 | UV12_C0010G0004 | Polymerase protein. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.774 |
KKS47611.1 | KKS46956.1 | UV12_C0006G0035 | UV12_C0014G0002 | Methionyl-tRNA formyltransferase. | Polymerase protein. | 0.712 |
KKS47611.1 | KKS47757.1 | UV12_C0006G0035 | UV12_C0005G0032 | Methionyl-tRNA formyltransferase. | Ribose-5-phosphate isomerase B. | 0.770 |
KKS47611.1 | KKS48069.1 | UV12_C0006G0035 | UV12_C0003G0028 | Methionyl-tRNA formyltransferase. | Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. | 0.817 |
KKS47611.1 | KKS48085.1 | UV12_C0006G0035 | UV12_C0003G0044 | Methionyl-tRNA formyltransferase. | Hypothetical protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.952 |
KKS47611.1 | KKS48086.1 | UV12_C0006G0035 | UV12_C0003G0045 | Methionyl-tRNA formyltransferase. | Hypothetical protein. | 0.587 |
KKS47611.1 | def | UV12_C0006G0035 | UV12_C0006G0036 | Methionyl-tRNA formyltransferase. | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 0.972 |
KKS47611.1 | rny | UV12_C0006G0035 | UV12_C0002G0071 | Methionyl-tRNA formyltransferase. | Ribonuclease Y; Endoribonuclease that initiates mRNA decay. Belongs to the RNase Y family. | 0.588 |
KKS47611.1 | thyA | UV12_C0006G0035 | UV12_C0010G0004 | Methionyl-tRNA formyltransferase. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.866 |
KKS47757.1 | KKS47611.1 | UV12_C0005G0032 | UV12_C0006G0035 | Ribose-5-phosphate isomerase B. | Methionyl-tRNA formyltransferase. | 0.770 |