STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KKQ56569.1Hypothetical protein. (112 aa)    
Predicted Functional Partners:
KKQ57419.1
Sensor protein resE.
  
 
  0.762
KKQ57199.1
PEP-CTERM system TPR-repeat lipoprotein.
  
 
 0.716
KKQ57803.1
Hypothetical protein.
  
 
 0.627
KKQ57214.1
DNA-binding response regulator.
  
 0.613
gyrB
Gyrase subunit B protein; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.613
topA
Topoisomerase protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...]
  
 
 0.607
KKQ55162.1
Conserved repeat domain protein.
  
 
 0.597
KKQ56570.1
Cell division protein; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
     
 0.542
KKQ56178.1
PAS/PAC sensor signal transduction histidine kinase.
    
  0.533
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
   
 
  0.501
Your Current Organism:
Parcubacteria group bacterium GW2011GWA23813b
NCBI taxonomy Id: 1618780
Other names: P. group bacterium GW2011_GWA2_38_13b, Parcubacteria group bacterium GW2011_GWA2_38_13b
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