STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpsL30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. (136 aa)    
Predicted Functional Partners:
KKQ57769.1
RNA binding S1 domain protein.
   
 0.999
rpsT
30S ribosomal protein S20; Binds directly to 16S ribosomal RNA.
   
 
 0.999
KKQ57629.1
Translation initiation factor IF-2.
  
 0.999
gltX
Glutamate-tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
   
 
 0.999
rpmE
Ribosomal protein L31 (Modular protein); Binds the 23S rRNA.
   
 
 0.999
rplY
50S ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
  
 
 0.999
rpsF
Hypothetical protein; Binds together with S18 to 16S ribosomal RNA.
  
 0.999
rpmF
Hypothetical protein; Belongs to the bacterial ribosomal protein bL32 family.
   
 
 0.999
KKQ57192.1
Hypothetical protein.
    
 
 0.999
rplU
50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
   
 
 0.999
Your Current Organism:
Parcubacteria group bacterium GW2011GWA23813b
NCBI taxonomy Id: 1618780
Other names: P. group bacterium GW2011_GWA2_38_13b, Parcubacteria group bacterium GW2011_GWA2_38_13b
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.