Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
glpXType II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; Derived by automated computational analysis using gene prediction method: Protein Homology. (335 aa)    
Predicted Functional Partners:
APT92491.1
Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the transketolase family.
   
 0.967
APT93328.1
Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
  
 
 0.940
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily.
    
 0.935
pgi
Glucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family.
     
 0.929
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
   
 
 0.923
APT92379.1
Phosphofructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family.
     
 0.907
APT93097.1
Mannose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.900
pgl
6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
     
 0.747
zwf
Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
      
 0.732
APT92209.1
Glucokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.727
Your Current Organism:
Corynebacterium phocae
NCBI taxonomy Id: 161895
Other names: C. phocae, CCUG 38205, CIP 105741, DSM 44612, JCM 12105, strain M408/89/1
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.