Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
AJI77582.1PFAM: Transmembrane domain of unknown function (DUF3566). (115 aa)    
Predicted Functional Partners:
gyrA
DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
  
    0.922
AJI78089.1
Hypothetical protein.
  
     0.593
AJI78856.1
PFAM: Bacterial PH domain.
  
    0.592
AJI80039.1
Putative integral membrane protein; PFAM: Protein of unknown function (DUF2029).
  
     0.524
AJI78989.1
PFAM: Protein of unknown function (DUF3186).
  
     0.488
AJI77627.1
Hypothetical protein.
  
     0.467
ctaF
Cytochrome c oxidase subunit IV; Part of cytochrome c oxidase, its function is unknown. Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
  
     0.466
rpfA
PFAM: Protein of unknown function (DUF3235); Transglycosylase-like domain.
   
    0.460
AJI79818.1
PFAM: Protein of unknown function (DUF3180).
  
     0.422
AJI79352.1
Hypothetical protein; Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA.
  
     0.419
Your Current Organism:
Corynebacterium singulare
NCBI taxonomy Id: 161899
Other names: C. singulare, CCUG 37330, CIP 105491, DSM 44357, IBS B52218, IFO 16162, JCM 10385, NBRC 16162
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