Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pbp2ACell division protein FtsI/penicillin-binding protein 2; PFAM: Penicillin binding protein transpeptidase domain. (476 aa)    
Predicted Functional Partners:
rodA
Cell elongation-specific peptidoglycan biosynthesis regulator RodA; PFAM: Cell cycle protein; Belongs to the SEDS family.
 
 0.998
pbp4
D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4); PFAM: D-Ala-D-Ala carboxypeptidase 3 (S13) family; TIGRFAM: D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family.
     
 0.959
dac
PFAM: D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family.
 
 
 0.954
AJI77601.1
PFAM: Protein kinase domain.
     
 0.944
pknB
PFAM: Protein kinase domain; PASTA domain.
 
   
 0.943
AJI79340.1
Cell division protein FtsI/penicillin-binding protein 2; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain.
  
  
0.942
AJI77605.1
FHA domain-containing protein; PFAM: FHA domain.
 
   
 0.918
ppp
PFAM: Protein phosphatase 2C.
  
  
 0.902
ftsW
Cell division-specific peptidoglycan biosynthesis regulator FtsW; PFAM: Cell cycle protein; TIGRFAM: cell division protein FtsW; Belongs to the SEDS family.
 
 0.884
AJI77606.1
PFAM: Protein of unknown function (DUF2662); FHA domain.
 
   
 0.854
Your Current Organism:
Corynebacterium singulare
NCBI taxonomy Id: 161899
Other names: C. singulare, CCUG 37330, CIP 105491, DSM 44357, IBS B52218, IFO 16162, JCM 10385, NBRC 16162
Server load: low (20%) [HD]