Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
irp2JABC-type multidrug transport system, ATPase and permease component; PFAM: ABC transporter. (574 aa)    
Predicted Functional Partners:
irp2K
ABC-type multidrug transport system, ATPase and permease component; PFAM: ABC transporter; ABC transporter transmembrane region.
 
  
 
0.986
metN
ABC-type metal ion transport system, ATPase component; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.
 
    
0.845
irp2L
Putative thioesterase involved in non-ribosomal peptide biosynthesis; PFAM: Thioesterase domain.
 
    0.789
irp2M
Glycosyl transferase, UDP-glucuronosyltransferase.
  
    0.719
trpE
PFAM: chorismate binding enzyme; Anthranilate synthase component I, N terminal region; TIGRFAM: anthranilate synthase component I, proteobacterial subset.
   
  
 0.688
irp2N
Acetyltransferase (isoleucine patch superfamily); PFAM: Bacterial transferase hexapeptide (six repeats); Maltose acetyltransferase.
       0.683
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
  0.657
irp2C
Amino acid adenylation enzyme/thioester reductase family protein; PFAM: Thioesterase domain; Phosphopantetheine attachment site; Methyltransferase domain; AMP-binding enzyme; Nonribosomal peptide synthase; Condensation domain; AMP-binding enzyme C-terminal domain; TIGRFAM: amino acid adenylation domain.
 
  
 0.630
irp2G
PFAM: Hypothetical bacterial integral membrane protein (Trep_Strep); TIGRFAM: conserved hypothetical integral membrane protein TIGR02185.
 
     0.576
irp2H
ABC-type cobalt transport system, permease component CbiQ; PFAM: Cobalt transport protein.
 
     0.560
Your Current Organism:
Corynebacterium singulare
NCBI taxonomy Id: 161899
Other names: C. singulare, CCUG 37330, CIP 105491, DSM 44357, IBS B52218, IFO 16162, JCM 10385, NBRC 16162
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