Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AJI78249.12-nitropropane dioxygenase precursor; PFAM: Nitronate monooxygenase. (323 aa)    
Predicted Functional Partners:
AJI78248.1
enoyl-CoA hydratase/carnithine racemase; PFAM: Enoyl-CoA hydratase/isomerase family.
 
  
 0.868
AJI77880.1
PFAM: Beta-ketoacyl synthase, C-terminal domain.
  
  
 0.813
fas-IB
Fatty acid synthase, bacterial type; PFAM: MaoC like domain; Acyl transferase domain; Domain of unknown function (DUF1729); Beta-ketoacyl synthase, N-terminal domain; Enoyl-(Acyl carrier protein) reductase; Beta-ketoacyl synthase, C-terminal domain.
  
  
 0.813
fas-IA
Fatty acid synthase, bacterial type; PFAM: MaoC like domain; Acyl transferase domain; Domain of unknown function (DUF1729); Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain.
  
  
 0.813
AJI78515.1
2-nitropropane dioxygenase-like enzyme; PFAM: Nitronate monooxygenase.
  
     0.728
AJI78250.1
PFAM: Thioesterase-like superfamily; TIGRFAM: acyl-CoA thioester hydrolase, YbgC/YbaW family.
   
   0.715
pks13
Mycolic acid condensase; PFAM: Thioesterase domain; Acyl transferase domain; Phosphopantetheine attachment site; Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain.
  
 
 0.688
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
      0.554
AJI78725.1
NUDIX family protein; PFAM: NUDIX domain.
  
     0.415
ssdA1
PFAM: Aldehyde dehydrogenase family.
       0.409
Your Current Organism:
Corynebacterium singulare
NCBI taxonomy Id: 161899
Other names: C. singulare, CCUG 37330, CIP 105491, DSM 44357, IBS B52218, IFO 16162, JCM 10385, NBRC 16162
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