| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AJI78427.1 | AJI78430.1 | CSING_04430 | CSING_04445 | PFAM: Glutaredoxin; TIGRFAM: Glutaredoxin-like protein. | Nucleoside-diphosphate-sugar epimerase; PFAM: NADH(P)-binding. | 0.580 |
| AJI78427.1 | AJI78431.1 | CSING_04430 | CSING_04450 | PFAM: Glutaredoxin; TIGRFAM: Glutaredoxin-like protein. | PFAM: Bacterial regulatory proteins, tetR family. | 0.408 |
| AJI78427.1 | folA | CSING_04430 | CSING_04435 | PFAM: Glutaredoxin; TIGRFAM: Glutaredoxin-like protein. | PFAM: Dihydrofolate reductase. | 0.839 |
| AJI78427.1 | thyA | CSING_04430 | CSING_04440 | PFAM: Glutaredoxin; TIGRFAM: Glutaredoxin-like protein. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.835 |
| AJI78430.1 | AJI78427.1 | CSING_04445 | CSING_04430 | Nucleoside-diphosphate-sugar epimerase; PFAM: NADH(P)-binding. | PFAM: Glutaredoxin; TIGRFAM: Glutaredoxin-like protein. | 0.580 |
| AJI78430.1 | AJI78431.1 | CSING_04445 | CSING_04450 | Nucleoside-diphosphate-sugar epimerase; PFAM: NADH(P)-binding. | PFAM: Bacterial regulatory proteins, tetR family. | 0.885 |
| AJI78430.1 | folA | CSING_04445 | CSING_04435 | Nucleoside-diphosphate-sugar epimerase; PFAM: NADH(P)-binding. | PFAM: Dihydrofolate reductase. | 0.608 |
| AJI78430.1 | thyA | CSING_04445 | CSING_04440 | Nucleoside-diphosphate-sugar epimerase; PFAM: NADH(P)-binding. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.586 |
| AJI78431.1 | AJI78427.1 | CSING_04450 | CSING_04430 | PFAM: Bacterial regulatory proteins, tetR family. | PFAM: Glutaredoxin; TIGRFAM: Glutaredoxin-like protein. | 0.408 |
| AJI78431.1 | AJI78430.1 | CSING_04450 | CSING_04445 | PFAM: Bacterial regulatory proteins, tetR family. | Nucleoside-diphosphate-sugar epimerase; PFAM: NADH(P)-binding. | 0.885 |
| AJI78431.1 | folA | CSING_04450 | CSING_04435 | PFAM: Bacterial regulatory proteins, tetR family. | PFAM: Dihydrofolate reductase. | 0.408 |
| AJI78431.1 | thyA | CSING_04450 | CSING_04440 | PFAM: Bacterial regulatory proteins, tetR family. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.408 |
| folA | AJI78427.1 | CSING_04435 | CSING_04430 | PFAM: Dihydrofolate reductase. | PFAM: Glutaredoxin; TIGRFAM: Glutaredoxin-like protein. | 0.839 |
| folA | AJI78430.1 | CSING_04435 | CSING_04445 | PFAM: Dihydrofolate reductase. | Nucleoside-diphosphate-sugar epimerase; PFAM: NADH(P)-binding. | 0.608 |
| folA | AJI78431.1 | CSING_04435 | CSING_04450 | PFAM: Dihydrofolate reductase. | PFAM: Bacterial regulatory proteins, tetR family. | 0.408 |
| folA | thyA | CSING_04435 | CSING_04440 | PFAM: Dihydrofolate reductase. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.999 |
| thyA | AJI78427.1 | CSING_04440 | CSING_04430 | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | PFAM: Glutaredoxin; TIGRFAM: Glutaredoxin-like protein. | 0.835 |
| thyA | AJI78430.1 | CSING_04440 | CSING_04445 | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | Nucleoside-diphosphate-sugar epimerase; PFAM: NADH(P)-binding. | 0.586 |
| thyA | AJI78431.1 | CSING_04440 | CSING_04450 | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | PFAM: Bacterial regulatory proteins, tetR family. | 0.408 |
| thyA | folA | CSING_04440 | CSING_04435 | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | PFAM: Dihydrofolate reductase. | 0.999 |