Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
lhrATP dependent helicase, Lhr family; PFAM: Helicase conserved C-terminal domain; DEAD/H associated; DEAD/DEAH box helicase. (1633 aa)    
Predicted Functional Partners:
nei
PFAM: Formamidopyrimidine-DNA glycosylase H2TH domain; Formamidopyrimidine-DNA glycosylase N-terminal domain.
 
  
 0.941
cysQ
3'(2'),5'-bisphosphate nucleotidase; PFAM: Inositol monophosphatase family.
       0.686
AJI78436.1
Putative membrane protein; PFAM: Domain of unknown function (DUF307).
       0.600
lldD
Alpha-hydroxyacid dehydrogenase, FMN-dependent L-lactate dehydrogenase; PFAM: FMN-dependent dehydrogenase.
       0.584
nei1
PFAM: Formamidopyrimidine-DNA glycosylase H2TH domain; Formamidopyrimidine-DNA glycosylase N-terminal domain; Zinc finger found in FPG and IleRS; TIGRFAM: DNA-formamidopyrimidine glycosylase; Belongs to the FPG family.
  
  
 0.578
radA
DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
   
    0.571
AJI79644.1
PFAM: Methylpurine-DNA glycosylase (MPG); TIGRFAM: DNA-3-methyladenine glycosylase (3mg); Belongs to the DNA glycosylase MPG family.
  
     0.434
mutM
DNA-(apurinic or apyrimidinic site) lyase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
  
  
 0.421
Your Current Organism:
Corynebacterium singulare
NCBI taxonomy Id: 161899
Other names: C. singulare, CCUG 37330, CIP 105491, DSM 44357, IBS B52218, IFO 16162, JCM 10385, NBRC 16162
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