STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fdnG2PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; TIGRFAM: formate dehydrogenase-N alpha subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (878 aa)    
Predicted Functional Partners:
fdnG1
PFAM: Molybdopterin oxidoreductase Fe4S4 domain.
 
 0.999
fdxH
Fe-S-cluster-containing hydrogenase subunit; PFAM: 4Fe-4S dicluster domain; 4Fe-4S binding domain.
 
 
 0.998
AJI78603.1
Formate-dependent nitrite reductase, membrane component; PFAM: Polysulphide reductase, NrfD.
 
     0.958
mdh
Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
     
 0.812
pflAC
PFAM: Glycine radical.
     
 0.809
pflB
Formate acetyltransferase 1; PFAM: Glycine radical; Pyruvate formate lyase; TIGRFAM: formate acetyltransferase 1.
     
 0.809
pckG
Phosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
     
 0.802
ppc
Phosphoenolpyruvate carboxylase, type 1; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family.
     
 0.800
pyc-1
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
     
  0.800
fumC
Fumarase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
     
  0.800
Your Current Organism:
Corynebacterium singulare
NCBI taxonomy Id: 161899
Other names: C. singulare, CCUG 37330, CIP 105491, DSM 44357, IBS B52218, IFO 16162, JCM 10385, NBRC 16162
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