Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
folP2Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (280 aa)    
Predicted Functional Partners:
folK
PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase.
 
 0.996
folX
Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
 
 
 0.993
folC
Folylpolyglutamate synthase/dihydrofolate synthase; PFAM: Mur ligase family, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: folylpolyglutamate synthase/dihydrofolate synthase.
 
 0.992
folE
PFAM: GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I.
  
 0.952
folP1
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
  
  
 
0.925
AJI79729.1
Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; PFAM: Aminotransferase class IV.
  
 
 0.916
AJI78631.1
PFAM: Glycosyl transferase family 2.
  
  
 0.871
dapE
Succinyldiaminopimelate desuccinylase; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: succinyl-diaminopimelate desuccinylase.
       0.832
AJI78629.1
TIGR00730 family protein; PFAM: Possible lysine decarboxylase; TIGRFAM: TIGR00725 family protein; TIGR00730 family protein; Belongs to the LOG family.
       0.832
AJI78632.1
TIGRFAM: DivIVA domain.
       0.832
Your Current Organism:
Corynebacterium singulare
NCBI taxonomy Id: 161899
Other names: C. singulare, CCUG 37330, CIP 105491, DSM 44357, IBS B52218, IFO 16162, JCM 10385, NBRC 16162
Server load: low (30%) [HD]