Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AJI78654.1DNA/RNA helicase, superfamily II; PFAM: Helicase conserved C-terminal domain; PLD-like domain; Type III restriction enzyme, res subunit; Domain of unknown function (DUF3427). (1038 aa)    
Predicted Functional Partners:
mutT
ADP-ribose pyrophosphatase; PFAM: NUDIX domain; TIGRFAM: mutator mutT protein.
 
     0.895
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.691
proY
Amino acid/polyamine/organocation transporter, APC superfamily; PFAM: Amino acid permease; TC 2.A.3.
       0.622
hutG
Formiminoglutamase; Catalyzes the conversion of N-formimidoyl-L-glutamate to L- glutamate and formamide; Belongs to the arginase family.
       0.618
dinG
DNA helicase, Rad3; PFAM: Helicase C-terminal domain; DEAD_2; DEAD/DEAH box helicase.
   
 0.593
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
  0.550
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
  0.528
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
  0.484
hsdM
Type I restriction-modification system methyltransferase subunit; PFAM: N-6 DNA Methylase; HsdM N-terminal domain.
 
   
 0.471
AJI80077.1
PFAM: Type I restriction modification DNA specificity domain.
 
    0.456
Your Current Organism:
Corynebacterium singulare
NCBI taxonomy Id: 161899
Other names: C. singulare, CCUG 37330, CIP 105491, DSM 44357, IBS B52218, IFO 16162, JCM 10385, NBRC 16162
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