Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
yagIPFAM: IclR helix-turn-helix domain; Bacterial transcriptional regulator. (242 aa)    
Predicted Functional Partners:
AJI78197.1
Biotin-dependent carboxylase-like protein; PFAM: Allophanate hydrolase subunit 2; Allophanate hydrolase subunit 1; TIGRFAM: sensor histidine kinase inhibitor, KipI family; biotin-dependent carboxylase uncharacterized domain.
  
    0.950
bktB
acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; Belongs to the thiolase-like superfamily. Thiolase family.
  
  
 0.852
AJI78658.1
Hypothetical protein; PFAM: Nucleoside recognition.
       0.803
hutH
Histidine ammonia-lyase; PFAM: Aromatic amino acid lyase; TIGRFAM: histidine ammonia-lyase.
 
   
 0.728
hutG
Formiminoglutamase; Catalyzes the conversion of N-formimidoyl-L-glutamate to L- glutamate and formamide; Belongs to the arginase family.
  
  
 0.599
hutI
Imidazolonepropionase; PFAM: Amidohydrolase; TIGRFAM: imidazolonepropionase.
 
   
 0.580
hutU
Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.
     
 0.512
whiH
PFAM: Bacterial regulatory proteins, gntR family; FCD domain.
 
  
 0.462
proY
Amino acid/polyamine/organocation transporter, APC superfamily; PFAM: Amino acid permease; TC 2.A.3.
       0.426
AJI78194.1
PFAM: Protein of unknown function (DUF1445); Belongs to the D-glutamate cyclase family.
  
    0.414
Your Current Organism:
Corynebacterium singulare
NCBI taxonomy Id: 161899
Other names: C. singulare, CCUG 37330, CIP 105491, DSM 44357, IBS B52218, IFO 16162, JCM 10385, NBRC 16162
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