STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hutHHistidine ammonia-lyase; PFAM: Aromatic amino acid lyase; TIGRFAM: histidine ammonia-lyase. (517 aa)    
Predicted Functional Partners:
hutU
Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.
 
 0.999
hutI
Imidazolonepropionase; PFAM: Amidohydrolase; TIGRFAM: imidazolonepropionase.
 
  
 0.991
hutG
Formiminoglutamase; Catalyzes the conversion of N-formimidoyl-L-glutamate to L- glutamate and formamide; Belongs to the arginase family.
 
  
 0.933
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
    
 0.923
yagI
PFAM: IclR helix-turn-helix domain; Bacterial transcriptional regulator.
 
   
 0.728
gcvP
PFAM: Glycine cleavage system P-protein; TIGRFAM: glycine dehydrogenase (decarboxylating); Belongs to the GcvP family.
   
  
 0.652
AJI78658.1
Hypothetical protein; PFAM: Nucleoside recognition.
 
     0.640
scrA
PTS system sucrose-specific IIC component; PFAM: Phosphotransferase system, EIIC; phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1; phosphotransferase system, EIIB; TIGRFAM: PTS system, sucrose-specific IIBC component; PTS system, glucose-like IIB component; PTS system, glucose subfamily, IIA component; Glc family (TC 4.A.1.2.12);PTS system sucrose-specific IIA component, Glc family (TC 4.A.1.2.12);PTS system sucrose-specific IIB component, Glc family (TC 4.A.1.2.12).
   
  
 0.447
ptsG
PTS system IIA component; PFAM: Phosphotransferase system, EIIC; phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1; phosphotransferase system, EIIB; TIGRFAM: PTS system, glucose subfamily, IIA component; Glc family (TC 4.A.1).
   
  
 0.447
nnrD
yjeF-like protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimer [...]
       0.441
Your Current Organism:
Corynebacterium singulare
NCBI taxonomy Id: 161899
Other names: C. singulare, CCUG 37330, CIP 105491, DSM 44357, IBS B52218, IFO 16162, JCM 10385, NBRC 16162
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