Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
lysGTranscriptional regulator, ArgP family; PFAM: LysR substrate binding domain; Bacterial regulatory helix-turn-helix protein, lysR family; TIGRFAM: transcriptional regulator, ArgP family. (294 aa)    
Predicted Functional Partners:
lysE
Lysine efflux permease; PFAM: LysE type translocator; TIGRFAM: L-lysine exporter.
 
   
 0.978
AJI78763.1
Putative membrane protein; PFAM: DoxX.
       0.765
lytR1
Transcriptional attenuator, LytR family; PFAM: Cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain.
   
    0.676
sufR
Transcriptional regulator; PFAM: Helix-turn-helix domain.
   
    0.588
kdpE
PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
   
  
 0.561
cobB1
NAD-dependent protein deacetylase, SIR2 family; PFAM: Sir2 family.
   
    0.539
cobB
NAD-dependent protein deacetylase, SIR2 family; PFAM: Sir2 family; Belongs to the sirtuin family. Class III subfamily.
   
    0.539
crp
cAMP-binding protein; PFAM: Crp-like helix-turn-helix domain; Cyclic nucleotide-binding domain.
   
 
 0.527
AJI78684.1
Transcriptional regulator; PFAM: IclR helix-turn-helix domain.
   
    0.482
AJI78765.1
PFAM: Winged helix DNA-binding domain.
  
    0.480
Your Current Organism:
Corynebacterium singulare
NCBI taxonomy Id: 161899
Other names: C. singulare, CCUG 37330, CIP 105491, DSM 44357, IBS B52218, IFO 16162, JCM 10385, NBRC 16162
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.