STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dnaQ3PFAM: Exonuclease. (207 aa)    
Predicted Functional Partners:
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 0.961
AJI78777.1
Putative signal-transduction protein; Contains cAMP-binding and CBS domains; PFAM: Putative nucleotidyltransferase substrate binding domain; CBS domain; Cyclic nucleotide-binding domain; Putative nucleotidyltransferase DUF294.
 
    0.961
AJI77754.1
PFAM: DNA polymerase III subunits gamma and tau domain III; DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, subunit gamma and tau.
   
 0.957
dnaE
PFAM: Bacterial DNA polymerase III alpha subunit; PHP domain; Helix-hairpin-helix motif; TIGRFAM: DNA-directed DNA polymerase III (polc).
   
 0.933
holA
PFAM: DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit.
    
 0.928
AJI79289.1
DNA polymerase III epsilon subunit-like 3'-5' exonuclease; PFAM: Exonuclease.
 
  
 0.923
AJI77836.1
PFAM: DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta' subunit.
   
  0.915
AJI77759.1
Hypothetical protein.
     
  0.900
dnaQ2
DNA polymerase III epsilon subunit-like 3'-5' exonuclease; PFAM: Exonuclease.
     
  0.900
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
       0.793
Your Current Organism:
Corynebacterium singulare
NCBI taxonomy Id: 161899
Other names: C. singulare, CCUG 37330, CIP 105491, DSM 44357, IBS B52218, IFO 16162, JCM 10385, NBRC 16162
Server load: medium (70%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.