Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
whiAHypothetical protein; Involved in cell division and chromosome segregation. (329 aa)    
Predicted Functional Partners:
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
 
 
   0.951
whiB2
Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
 
 
 0.926
rbpA
Protein of unknown function (DUF4109); Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. Belongs to the RNA polymerase-binding protein RbpA family.
  
 
 
 0.915
AJI78859.1
Conserved hypothetical protein, cofD-related; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family.
 
  
 0.880
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
   0.879
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.856
rpoD
RNA polymerase sigma factor, sigma-70 family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
 
 
 0.826
sigB
RNA polymerase sigma factor, sigma-70 family; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
    
 
 0.796
AJI79105.1
PFAM: Domain of unknown function (DUF4193).
  
     0.761
AJI78858.1
Putative P-loop-containing kinase; Displays ATPase and GTPase activities.
 
  
 0.755
Your Current Organism:
Corynebacterium singulare
NCBI taxonomy Id: 161899
Other names: C. singulare, CCUG 37330, CIP 105491, DSM 44357, IBS B52218, IFO 16162, JCM 10385, NBRC 16162
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