STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
xerDTyrosine recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. (292 aa)    
Predicted Functional Partners:
AJI78988.1
NTP pyrophosphohydrolase; PFAM: NUDIX domain.
  
  
 0.853
AJI78990.1
Putative membrane-anchored protein; PFAM: Thiamine pyrophosphokinase C terminal.
 
    0.773
AJI78986.1
Hypothetical protein.
       0.756
recN
DNA replication and repair protein RecN; May be involved in recombinational repair of damaged DNA.
 
   
 0.756
AJI78989.1
PFAM: Protein of unknown function (DUF3186).
  
    0.745
AJI78985.1
ATPase involved in chromosome partitioning; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain.
 
   
 0.699
AJI79168.1
DNA segregation ATPase, FtsK/SpoIIIE family; PFAM: Ftsk gamma domain; FtsK/SpoIIIE family; Domain of unknown function (DUF4117).
  
   
 0.680
tlyA
PFAM: FtsJ-like methyltransferase; S4 domain; TIGRFAM: TlyA family rRNA methyltransferase/putative hemolysin.
  
    0.635
ppnK
Putative sugar kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
       0.628
apt
PRPP-binding protein, adenine/guanine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
    0.612
Your Current Organism:
Corynebacterium singulare
NCBI taxonomy Id: 161899
Other names: C. singulare, CCUG 37330, CIP 105491, DSM 44357, IBS B52218, IFO 16162, JCM 10385, NBRC 16162
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