Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
tpxThiol peroxidase (atypical 2-Cys peroxiredoxin); Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily. (182 aa)    
Predicted Functional Partners:
hisS
PFAM: Anticodon binding domain; Histidyl-tRNA synthetase; TIGRFAM: histidyl-tRNA synthetase.
       0.832
AJI79061.1
Zn-dependent hydrolase, glyoxylase; PFAM: Metallo-beta-lactamase superfamily.
       0.832
sodA
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
  
 0.747
lepB
PFAM: Peptidase S24-like; Signal peptidase, peptidase S26; TIGRFAM: signal peptidase I, bacterial type; Belongs to the peptidase S26 family.
   
    0.736
lepB2
PFAM: Peptidase S24-like; Signal peptidase, peptidase S26; TIGRFAM: signal peptidase I, bacterial type; Belongs to the peptidase S26 family.
   
    0.736
ppiB
PFAM: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD.
  
    0.721
AJI79064.1
Hypothetical protein.
       0.514
AJI79127.1
Peroxiredoxin; PFAM: AhpC/TSA family.
  
  
 0.455
trxA
PFAM: Thioredoxin; TIGRFAM: thioredoxin; Belongs to the thioredoxin family.
  
 
 0.447
gcvP
PFAM: Glycine cleavage system P-protein; TIGRFAM: glycine dehydrogenase (decarboxylating); Belongs to the GcvP family.
       0.445
Your Current Organism:
Corynebacterium singulare
NCBI taxonomy Id: 161899
Other names: C. singulare, CCUG 37330, CIP 105491, DSM 44357, IBS B52218, IFO 16162, JCM 10385, NBRC 16162
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