STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
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[Homology]
Score
ptsIPhosphoenolpyruvate--protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (561 aa)    
Predicted Functional Partners:
ptsH
PFAM: PTS HPr component phosphorylation site; TIGRFAM: Phosphotransferase System HPr (HPr) Family.
 
 0.999
ptsF
PTS system D-fructose-specific IIA component; PFAM: Phosphotransferase system, EIIC; PTS system, Lactose/Cellobiose specific IIB subunit; Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; TIGRFAM: PTS system, fructose-specific, IIB component; PTS system, fructose subfamily, IIC component; PTS system, fructose subfamily, IIA component; F1P-forming; Frc family (TC 4.A.2.1.4);PTS system D-fructose-specific IIB component (F1P-forming), Frc family (TC 4.A.2.1.4);PTS system D-fructose-specific IIC component (F1P-forming), Frc family (TC 4.A.2.1.4).
 
  
 0.998
ptsG
PTS system IIA component; PFAM: Phosphotransferase system, EIIC; phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1; phosphotransferase system, EIIB; TIGRFAM: PTS system, glucose subfamily, IIA component; Glc family (TC 4.A.1).
 
 0.985
scrA
PTS system sucrose-specific IIC component; PFAM: Phosphotransferase system, EIIC; phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1; phosphotransferase system, EIIB; TIGRFAM: PTS system, sucrose-specific IIBC component; PTS system, glucose-like IIB component; PTS system, glucose subfamily, IIA component; Glc family (TC 4.A.1.2.12);PTS system sucrose-specific IIA component, Glc family (TC 4.A.1.2.12);PTS system sucrose-specific IIB component, Glc family (TC 4.A.1.2.12).
 
 0.964
dhaM
Phosphocarrier protein HPr/dihydroxyacetone kinase DhaM subunit; PFAM: PTS system fructose IIA component; PTS HPr component phosphorylation site; TIGRFAM: dihydroxyacetone kinase, phosphotransfer subunit; Phosphotransferase System HPr (HPr) Family.
   
 0.958
fruK
1-phosphofructokinase; PFAM: pfkB family carbohydrate kinase; TIGRFAM: 1-phosphofructokinase; hexose kinase, 1-phosphofructokinase family.
 
  
 0.942
nagE
PTS system N-acetylglucosamine-specific IIA component; PFAM: Phosphotransferase system, EIIC; phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1; phosphotransferase system, EIIB; TIGRFAM: PTS system, glucose-like IIB component; PTS system, N-acetylglucosamine-specific IIBC component; PTS system, glucose subfamily, IIA component; Glc family /PTS system N-acetylglucosamine-specific IIB component, Glc family (TC 4.A.1.1.2)/PTS system N-acetylglucosamine-specific IIC component, Glc family (TC 4.A.1.1.2).
  
 0.736
sugR
Transcriptional regulator, DeoR family; PFAM: DeoR-like helix-turn-helix domain; DeoR C terminal sensor domain.
 
  
 0.516
tuf
Translation elongation factor 1A (EF-1A/EF-Tu); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
   
    0.471
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
  
 0.459
Your Current Organism:
Corynebacterium singulare
NCBI taxonomy Id: 161899
Other names: C. singulare, CCUG 37330, CIP 105491, DSM 44357, IBS B52218, IFO 16162, JCM 10385, NBRC 16162
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