Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ptsFPTS system D-fructose-specific IIA component; PFAM: Phosphotransferase system, EIIC; PTS system, Lactose/Cellobiose specific IIB subunit; Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; TIGRFAM: PTS system, fructose-specific, IIB component; PTS system, fructose subfamily, IIC component; PTS system, fructose subfamily, IIA component; F1P-forming; Frc family (TC 4.A.2.1.4);PTS system D-fructose-specific IIB component (F1P-forming), Frc family (TC 4.A.2.1.4);PTS system D-fructose-specific IIC component (F1P-forming), Frc family (TC 4.A.2.1.4). (706 aa)    
Predicted Functional Partners:
fruK
1-phosphofructokinase; PFAM: pfkB family carbohydrate kinase; TIGRFAM: 1-phosphofructokinase; hexose kinase, 1-phosphofructokinase family.
 
 
 0.999
ptsH
PFAM: PTS HPr component phosphorylation site; TIGRFAM: Phosphotransferase System HPr (HPr) Family.
 
 
 0.999
scrA
PTS system sucrose-specific IIC component; PFAM: Phosphotransferase system, EIIC; phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1; phosphotransferase system, EIIB; TIGRFAM: PTS system, sucrose-specific IIBC component; PTS system, glucose-like IIB component; PTS system, glucose subfamily, IIA component; Glc family (TC 4.A.1.2.12);PTS system sucrose-specific IIA component, Glc family (TC 4.A.1.2.12);PTS system sucrose-specific IIB component, Glc family (TC 4.A.1.2.12).
 
  
 0.993
ptsG
PTS system IIA component; PFAM: Phosphotransferase system, EIIC; phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1; phosphotransferase system, EIIB; TIGRFAM: PTS system, glucose subfamily, IIA component; Glc family (TC 4.A.1).
 
  
 0.992
ptsI
Phosphoenolpyruvate--protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
  
 0.990
fba
Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
  
 
 0.988
sugR
Transcriptional regulator, DeoR family; PFAM: DeoR-like helix-turn-helix domain; DeoR C terminal sensor domain.
 
  
 0.985
nagE
PTS system N-acetylglucosamine-specific IIA component; PFAM: Phosphotransferase system, EIIC; phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1; phosphotransferase system, EIIB; TIGRFAM: PTS system, glucose-like IIB component; PTS system, N-acetylglucosamine-specific IIBC component; PTS system, glucose subfamily, IIA component; Glc family /PTS system N-acetylglucosamine-specific IIB component, Glc family (TC 4.A.1.1.2)/PTS system N-acetylglucosamine-specific IIC component, Glc family (TC 4.A.1.1.2).
 
  
 0.957
cscK
Sugar kinase, ribokinase; PFAM: pfkB family carbohydrate kinase.
    
 0.953
arbG
Transcriptional antiterminator, BglG family; PFAM: CAT RNA binding domain; PRD domain.
 
  
 0.944
Your Current Organism:
Corynebacterium singulare
NCBI taxonomy Id: 161899
Other names: C. singulare, CCUG 37330, CIP 105491, DSM 44357, IBS B52218, IFO 16162, JCM 10385, NBRC 16162
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