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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ptsHPFAM: PTS HPr component phosphorylation site; TIGRFAM: Phosphotransferase System HPr (HPr) Family. (89 aa)    
Predicted Functional Partners:
ptsI
Phosphoenolpyruvate--protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
 0.999
ptsF
PTS system D-fructose-specific IIA component; PFAM: Phosphotransferase system, EIIC; PTS system, Lactose/Cellobiose specific IIB subunit; Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; TIGRFAM: PTS system, fructose-specific, IIB component; PTS system, fructose subfamily, IIC component; PTS system, fructose subfamily, IIA component; F1P-forming; Frc family (TC 4.A.2.1.4);PTS system D-fructose-specific IIB component (F1P-forming), Frc family (TC 4.A.2.1.4);PTS system D-fructose-specific IIC component (F1P-forming), Frc family (TC 4.A.2.1.4).
 
 
 0.999
ptsG
PTS system IIA component; PFAM: Phosphotransferase system, EIIC; phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1; phosphotransferase system, EIIB; TIGRFAM: PTS system, glucose subfamily, IIA component; Glc family (TC 4.A.1).
 
 0.991
scrA
PTS system sucrose-specific IIC component; PFAM: Phosphotransferase system, EIIC; phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1; phosphotransferase system, EIIB; TIGRFAM: PTS system, sucrose-specific IIBC component; PTS system, glucose-like IIB component; PTS system, glucose subfamily, IIA component; Glc family (TC 4.A.1.2.12);PTS system sucrose-specific IIA component, Glc family (TC 4.A.1.2.12);PTS system sucrose-specific IIB component, Glc family (TC 4.A.1.2.12).
  
 0.987
nagE
PTS system N-acetylglucosamine-specific IIA component; PFAM: Phosphotransferase system, EIIC; phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1; phosphotransferase system, EIIB; TIGRFAM: PTS system, glucose-like IIB component; PTS system, N-acetylglucosamine-specific IIBC component; PTS system, glucose subfamily, IIA component; Glc family /PTS system N-acetylglucosamine-specific IIB component, Glc family (TC 4.A.1.1.2)/PTS system N-acetylglucosamine-specific IIC component, Glc family (TC 4.A.1.1.2).
 
 
 0.948
fruK
1-phosphofructokinase; PFAM: pfkB family carbohydrate kinase; TIGRFAM: 1-phosphofructokinase; hexose kinase, 1-phosphofructokinase family.
 
  
 0.915
AJI79774.1
PFAM: Bacterial regulatory proteins, lacI family; Periplasmic binding protein-like domain.
   
 
 0.777
rpsG
SSU ribosomal protein S7P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
  
    0.666
tuf
Translation elongation factor 1A (EF-1A/EF-Tu); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
   
  
 0.601
sugR
Transcriptional regulator, DeoR family; PFAM: DeoR-like helix-turn-helix domain; DeoR C terminal sensor domain.
 
  
 0.546
Your Current Organism:
Corynebacterium singulare
NCBI taxonomy Id: 161899
Other names: C. singulare, CCUG 37330, CIP 105491, DSM 44357, IBS B52218, IFO 16162, JCM 10385, NBRC 16162
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