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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Score
thiOGlycine oxidase; PFAM: FAD dependent oxidoreductase; TIGRFAM: glycine oxidase ThiO. (381 aa)    
Predicted Functional Partners:
thiG
Thiazole-phosphate synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
 0.999
AJI79233.1
PFAM: ThiS family; TIGRFAM: thiamine biosynthesis protein ThiS.
 
  
 0.897
theD
PFAM: Phosphomethylpyrimidine kinase; TIGRFAM: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase.
  
  
 0.890
thiC
Hydroxymethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
  
  
 0.857
thiE
Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
  
  
 0.848
gcvT
Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine.
  
 
 0.822
thiF
Dinucleotide-utilizing enzyme possibly involved in molybdopterin or thiamin biosynthesis; PFAM: MoeZ/MoeB domain; ThiF family.
 
  
 0.818
thiL
Thiamine-phosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
      
 0.624
rplS
LSU ribosomal protein L19P; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
       0.585
lldD
Alpha-hydroxyacid dehydrogenase, FMN-dependent L-lactate dehydrogenase; PFAM: FMN-dependent dehydrogenase.
   
 
 0.498
Your Current Organism:
Corynebacterium singulare
NCBI taxonomy Id: 161899
Other names: C. singulare, CCUG 37330, CIP 105491, DSM 44357, IBS B52218, IFO 16162, JCM 10385, NBRC 16162
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