Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AJI79289.1DNA polymerase III epsilon subunit-like 3'-5' exonuclease; PFAM: Exonuclease. (457 aa)    
Predicted Functional Partners:
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.959
AJI77754.1
PFAM: DNA polymerase III subunits gamma and tau domain III; DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, subunit gamma and tau.
   
 0.959
AJI77759.1
Hypothetical protein.
 
  
 0.954
dnaE
PFAM: Bacterial DNA polymerase III alpha subunit; PHP domain; Helix-hairpin-helix motif; TIGRFAM: DNA-directed DNA polymerase III (polc).
  
 0.954
holA
PFAM: DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit.
    
 0.946
dnaQ3
PFAM: Exonuclease.
 
  
 0.940
AJI77836.1
PFAM: DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta' subunit.
   
 0.929
dnaQ2
DNA polymerase III epsilon subunit-like 3'-5' exonuclease; PFAM: Exonuclease.
 
  
 0.915
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.887
AJI78850.1
tRNA/rRNA cytosine-C5-methylase; PFAM: NOL1/NOP2/sun family; NusB family; TIGRFAM: 16S rRNA (cytosine(967)-C(5))-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
  
 
 0.856
Your Current Organism:
Corynebacterium singulare
NCBI taxonomy Id: 161899
Other names: C. singulare, CCUG 37330, CIP 105491, DSM 44357, IBS B52218, IFO 16162, JCM 10385, NBRC 16162
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.