Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
dnaEPFAM: Bacterial DNA polymerase III alpha subunit; PHP domain; Helix-hairpin-helix motif; TIGRFAM: DNA-directed DNA polymerase III (polc). (1191 aa)    
Predicted Functional Partners:
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 0.988
AJI77754.1
PFAM: DNA polymerase III subunits gamma and tau domain III; DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, subunit gamma and tau.
 
 0.986
AJI77836.1
PFAM: DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta' subunit.
  
 
 0.984
holA
PFAM: DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit.
  
 0.984
AJI79289.1
DNA polymerase III epsilon subunit-like 3'-5' exonuclease; PFAM: Exonuclease.
  
 0.954
AJI77759.1
Hypothetical protein.
   
 0.944
dnaQ2
DNA polymerase III epsilon subunit-like 3'-5' exonuclease; PFAM: Exonuclease.
   
 0.939
dnaQ3
PFAM: Exonuclease.
   
 0.939
secA1
Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
  
   
 0.705
rarD
rarD protein; PFAM: EamA-like transporter family; TIGRFAM: rarD protein.
     
 0.703
Your Current Organism:
Corynebacterium singulare
NCBI taxonomy Id: 161899
Other names: C. singulare, CCUG 37330, CIP 105491, DSM 44357, IBS B52218, IFO 16162, JCM 10385, NBRC 16162
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