Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
AJI79423.1PFAM: Protein of unknown function (DUF2786). (357 aa)    
Predicted Functional Partners:
AJI79424.1
Hypothetical protein; PFAM: CYTH domain; CHAD domain.
 
     0.807
glnE
Glutamine synthetase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transducti [...]
       0.641
glnA2
PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase, beta-Grasp domain; TIGRFAM: glutamine synthetase, type I.
       0.641
AJI78481.1
Putative integral membrane protein; PFAM: Putative zinc-finger.
  
     0.616
AJI78664.1
Hypothetical protein.
  
     0.584
AJI79627.1
PFAM: FAD-NAD(P)-binding.
  
     0.558
AJI79856.1
PFAM: Acetyltransferase (GNAT) family.
  
     0.525
AJI78278.1
TIGRFAM: TIGR03089 family protein.
  
     0.509
AJI78059.1
PFAM: Proteins of 100 residues with WXG; TIGRFAM: WXG100 family type VII secretion target; Belongs to the WXG100 family.
  
     0.507
AJI79696.1
Protein-disulfide isomerase; PFAM: Thioredoxin.
  
     0.496
Your Current Organism:
Corynebacterium singulare
NCBI taxonomy Id: 161899
Other names: C. singulare, CCUG 37330, CIP 105491, DSM 44357, IBS B52218, IFO 16162, JCM 10385, NBRC 16162
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