Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AJI79424.1Hypothetical protein; PFAM: CYTH domain; CHAD domain. (574 aa)    
Predicted Functional Partners:
AJI79423.1
PFAM: Protein of unknown function (DUF2786).
 
     0.807
AJI79794.1
Hypothetical protein.
  
     0.587
glnE
Glutamine synthetase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transducti [...]
       0.537
glnA2
PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase, beta-Grasp domain; TIGRFAM: glutamine synthetase, type I.
       0.537
AJI79420.1
Hypothetical protein.
       0.467
AJI77823.1
PFAM: Type II secretion system (T2SS), protein F.
  
     0.453
AJI79001.1
PFAM: von Willebrand factor type A domain; Bacterial extracellular solute-binding protein.
  
     0.424
AJI78769.1
PFAM: Bacterial PH domain.
  
     0.413
AJI78394.1
PFAM: Helicase conserved C-terminal domain.
 
     0.412
AJI79952.1
Putative integral membrane protein; PFAM: Uncharacterised protein family (UPF0104); TIGRFAM: conserved hypothetical protein.
  
     0.400
Your Current Organism:
Corynebacterium singulare
NCBI taxonomy Id: 161899
Other names: C. singulare, CCUG 37330, CIP 105491, DSM 44357, IBS B52218, IFO 16162, JCM 10385, NBRC 16162
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