STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cas1CRISPR-associated endonuclease Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (312 aa)    
Predicted Functional Partners:
casA
PFAM: CRISPR-associated protein (Cas_Cas2CT1978); TIGRFAM: CRISPR-associated endoribonuclease Cas2, subtype I-E/ECOLI.
 
 
 0.999
casC
Subtype I-E/ECOLI; PFAM: CRISPR associated protein; TIGRFAM: CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI.
 
  
 0.971
casE
PFAM: CT1975-like protein; TIGRFAM: CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI.
 
  
 0.964
casD
CRISPR-associated protein, Cas5e family; PFAM: CRISPR-associated protein (Cas_Cas5); TIGRFAM: CRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI; CRISPR-associated protein Cas5, N-terminal domain.
 
   
 0.961
casF
PFAM: CRISPR-associated protein Cse1 (CRISPR_cse1); TIGRFAM: CRISPR type I-E/ECOLI-associated protein CasA/Cse1.
 
  
 0.956
AJI79457.1
PFAM: CRISPR-associated protein Cse2 (CRISPR_cse2); TIGRFAM: CRISPR type I-E/ECOLI-associated protein CasB/Cse2.
 
  
 0.937
casG
PFAM: DEAD/DEAH box helicase; TIGRFAM: CRISPR-associated helicase Cas3; CRISPR-associated endonuclease Cas3-HD.
 
  
 0.923
Your Current Organism:
Corynebacterium singulare
NCBI taxonomy Id: 161899
Other names: C. singulare, CCUG 37330, CIP 105491, DSM 44357, IBS B52218, IFO 16162, JCM 10385, NBRC 16162
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.