Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
sirR2PFAM: FeoA domain; Iron dependent repressor, metal binding and dimerisation domain; Iron dependent repressor, N-terminal DNA binding domain. (226 aa)    
Predicted Functional Partners:
mntC
ABC-type Mn2+/Zn2+ transport system, permease component; PFAM: ABC 3 transport family.
  
 0.776
lepB
PFAM: Peptidase S24-like; Signal peptidase, peptidase S26; TIGRFAM: signal peptidase I, bacterial type; Belongs to the peptidase S26 family.
   
    0.562
lepB2
PFAM: Peptidase S24-like; Signal peptidase, peptidase S26; TIGRFAM: signal peptidase I, bacterial type; Belongs to the peptidase S26 family.
   
    0.562
clpP2
ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
       0.547
AJI79349.1
Hypothetical protein.
   
    0.517
clpP1
ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
       0.505
AJI80109.1
Putative transcriptional regulator; PFAM: Uncharacterized ACR, COG1678; Belongs to the UPF0301 (AlgH) family.
   
    0.505
nrdI1
Ribonucleoside-diphosphate reductase 2, operon protein nrdI; Probably involved in ribonucleotide reductase function.
     
 0.501
AJI79663.1
Membrane protease subunit, stomatin/prohibitin; PFAM: SPFH domain / Band 7 family.
  
    0.485
mntA
ABC-type metal ion transport system, periplasmic component/surface adhesin; PFAM: Periplasmic solute binding protein family; Belongs to the bacterial solute-binding protein 9 family.
 
  
 0.466
Your Current Organism:
Corynebacterium singulare
NCBI taxonomy Id: 161899
Other names: C. singulare, CCUG 37330, CIP 105491, DSM 44357, IBS B52218, IFO 16162, JCM 10385, NBRC 16162
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