STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nrdF1PFAM: Ribonucleotide reductase, small chain; TIGRFAM: ribonucleoside-diphosphate reductase, class 1b, beta subunit. (341 aa)    
Predicted Functional Partners:
nrdE1
Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
 
 0.999
nrdE2
Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
 
 0.997
nrdI1
Ribonucleoside-diphosphate reductase 2, operon protein nrdI; Probably involved in ribonucleotide reductase function.
 
 
 0.979
nrdI2
Ribonucleoside-diphosphate reductase 2, operon protein nrdI; Probably involved in ribonucleotide reductase function.
 
 
 0.960
tmk
PFAM: Thymidylate kinase; TIGRFAM: dTMP kinase.
   
 
 0.907
cmk
PFAM: Cytidylate kinase; TIGRFAM: cytidylate kinase.
    
 0.907
adk
Adenylate kinase-like kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
     
 0.906
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
     
 0.906
AJI78116.1
PFAM: Pyruvate kinase, barrel domain.
     
 0.903
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
     
 0.903
Your Current Organism:
Corynebacterium singulare
NCBI taxonomy Id: 161899
Other names: C. singulare, CCUG 37330, CIP 105491, DSM 44357, IBS B52218, IFO 16162, JCM 10385, NBRC 16162
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