Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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pncB1Putative nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (450 aa)    
Predicted Functional Partners:
pncA
Nicotinamidase-like amidase; PFAM: Isochorismatase family.
 
 0.996
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
 
  
 0.952
cinA
PFAM: Competence-damaged protein; TIGRFAM: amidohydrolase, PncC family; Belongs to the CinA family.
  
 
 0.925
AJI78327.1
Zn-finger containing NTP pyrophosphohydrolase; PFAM: NUDIX domain.
    
 0.907
AJI79068.1
5'-nucleotidase/2',3'-cyclic phosphodiesterase-like hydrolase; PFAM: 5'-nucleotidase, C-terminal domain; Belongs to the 5'-nucleotidase family.
    
 0.904
nagD
Putative sugar phosphatase of HAD superfamily; PFAM: HAD-hyrolase-like; Haloacid dehalogenase-like hydrolase; TIGRFAM: HAD-superfamily subfamily IIA hydrolase, TIGR01457; Haloacid Dehalogenase Superfamily Class (subfamily) IIA; Belongs to the HAD-like hydrolase superfamily.
     
  0.900
AJI79680.1
Hypothetical protein.
       0.736
dinG
DNA helicase, Rad3; PFAM: Helicase C-terminal domain; DEAD_2; DEAD/DEAH box helicase.
       0.724
clpS
Hypothetical protein; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.
     
 0.629
AJI79677.1
L-aminopeptidase/D-esterase; PFAM: Peptidase family S58.
       0.603
Your Current Organism:
Corynebacterium singulare
NCBI taxonomy Id: 161899
Other names: C. singulare, CCUG 37330, CIP 105491, DSM 44357, IBS B52218, IFO 16162, JCM 10385, NBRC 16162
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