STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nrdE2Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (720 aa)    
Predicted Functional Partners:
nrdF2
Ribonucleoside-diphosphate reductase class Ib beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.
 
 0.999
nrdF1
PFAM: Ribonucleotide reductase, small chain; TIGRFAM: ribonucleoside-diphosphate reductase, class 1b, beta subunit.
 
 0.997
AJI79690.1
Ribonucleoside-diphosphate reductase class Ib glutaredoxin subunit; PFAM: Glutaredoxin; TIGRFAM: Glutaredoxin-like protein NrdH.
 
 0.981
nrdI2
Ribonucleoside-diphosphate reductase 2, operon protein nrdI; Probably involved in ribonucleotide reductase function.
 
  
 0.973
nrdI1
Ribonucleoside-diphosphate reductase 2, operon protein nrdI; Probably involved in ribonucleotide reductase function.
 
  
 0.944
AJI80109.1
Putative transcriptional regulator; PFAM: Uncharacterized ACR, COG1678; Belongs to the UPF0301 (AlgH) family.
   
 0.936
adk
Adenylate kinase-like kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
     
 0.919
tmk
PFAM: Thymidylate kinase; TIGRFAM: dTMP kinase.
  
 
 0.919
cmk
PFAM: Cytidylate kinase; TIGRFAM: cytidylate kinase.
  
 
 0.911
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
     
 0.906
Your Current Organism:
Corynebacterium singulare
NCBI taxonomy Id: 161899
Other names: C. singulare, CCUG 37330, CIP 105491, DSM 44357, IBS B52218, IFO 16162, JCM 10385, NBRC 16162
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