Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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dusPutative TIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (384 aa)    
Predicted Functional Partners:
AJI78163.1
MAF protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
 
     0.689
phoU
PFAM: PhoU domain; TIGRFAM: phosphate transport system regulatory protein PhoU.
       0.674
cat1
PFAM: Acetyl-CoA hydrolase/transferase C-terminal domain; Acetyl-CoA hydrolase/transferase N-terminal domain; TIGRFAM: succinate CoA transferase.
       0.636
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
 
 
 
 0.612
fdxC
Ferredoxin; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
   
  
 0.563
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
   
  
 0.554
AJI78850.1
tRNA/rRNA cytosine-C5-methylase; PFAM: NOL1/NOP2/sun family; NusB family; TIGRFAM: 16S rRNA (cytosine(967)-C(5))-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
 
 
 0.487
trmB
tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
 
 
 0.465
theD
PFAM: Phosphomethylpyrimidine kinase; TIGRFAM: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase.
       0.458
truA
tRNA pseudouridine(38-40) synthase; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
  
 
 0.433
Your Current Organism:
Corynebacterium singulare
NCBI taxonomy Id: 161899
Other names: C. singulare, CCUG 37330, CIP 105491, DSM 44357, IBS B52218, IFO 16162, JCM 10385, NBRC 16162
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