Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
tcsS1PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phospho-acceptor) domain. (482 aa)    
Predicted Functional Partners:
tcrX
PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
 
 
 0.967
mprA
PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
 
 0.860
mtrA
PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
 
 0.854
regX3
PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
 
 
 0.846
kdpE
PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
 
 
 0.793
AJI79764.1
Putative transcriptional regulator; PFAM: TipAS antibiotic-recognition domain; MerR HTH family regulatory protein.
       0.628
AJI79765.1
Major facilitator superfamily permease; PFAM: Vacuole effluxer Atg22 like.
       0.544
AJI78467.1
Trypsin-like serine protease with C-terminal PDZ domain; PFAM: Trypsin-like peptidase domain; PDZ domain.
 
  
 0.454
Your Current Organism:
Corynebacterium singulare
NCBI taxonomy Id: 161899
Other names: C. singulare, CCUG 37330, CIP 105491, DSM 44357, IBS B52218, IFO 16162, JCM 10385, NBRC 16162
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