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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lytR1Transcriptional attenuator, LytR family; PFAM: Cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain. (468 aa)    
Predicted Functional Partners:
sufR
Transcriptional regulator; PFAM: Helix-turn-helix domain.
  
    0.705
AJI79995.1
Amidase, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit; PFAM: Amidase; Belongs to the amidase family.
       0.694
AJI79996.1
PFAM: CAAX protease self-immunity.
       0.694
kdpE
PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
   
  
 0.686
lysG
Transcriptional regulator, ArgP family; PFAM: LysR substrate binding domain; Bacterial regulatory helix-turn-helix protein, lysR family; TIGRFAM: transcriptional regulator, ArgP family.
   
    0.665
AJI79993.1
Fructose-2,6-bisphosphatase; PFAM: Histidine phosphatase superfamily (branch 1); Belongs to the phosphoglycerate mutase family.
 
     0.656
cobB1
NAD-dependent protein deacetylase, SIR2 family; PFAM: Sir2 family.
   
    0.632
cobB
NAD-dependent protein deacetylase, SIR2 family; PFAM: Sir2 family; Belongs to the sirtuin family. Class III subfamily.
   
    0.632
pheA
PFAM: Prephenate dehydratase; ACT domain.
     
 0.613
AJI80109.1
Putative transcriptional regulator; PFAM: Uncharacterized ACR, COG1678; Belongs to the UPF0301 (AlgH) family.
  
    0.587
Your Current Organism:
Corynebacterium singulare
NCBI taxonomy Id: 161899
Other names: C. singulare, CCUG 37330, CIP 105491, DSM 44357, IBS B52218, IFO 16162, JCM 10385, NBRC 16162
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