Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AJI80064.1Osmosensitive K+ channel histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Domain of unknown function (DUF4118); His Kinase A (phospho-acceptor) domain; Universal stress protein family; Osmosensitive K+ channel His kinase sensor domain. (865 aa)    
Predicted Functional Partners:
kdpE
PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
 
 0.998
kdpC
K+-transporting ATPase, c chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
 
  
 0.991
kdpB
K+-transporting ATPase, B subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
 
  
 0.973
kdpA
K+-transporting ATPase, KdpA; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane.
 
  
 0.969
mtrA
PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
  
 
 0.632
pheT
phenylalanyl-tRNA synthetase beta subunit; PFAM: tRNA synthetase B5 domain; Ferredoxin-fold anticodon binding domain; B3/4 domain; Putative tRNA binding domain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit, non-spirochete bacterial; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
       0.589
regX3
PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
  
 
 0.487
mprA
PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
  
 
 0.487
tcrX
PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
  
 
 0.487
AJI80062.1
SNF family Na+-dependent transporter; PFAM: Sodium:neurotransmitter symporter family; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
       0.474
Your Current Organism:
Corynebacterium singulare
NCBI taxonomy Id: 161899
Other names: C. singulare, CCUG 37330, CIP 105491, DSM 44357, IBS B52218, IFO 16162, JCM 10385, NBRC 16162
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