node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KKQ41245.1 | KKQ41349.1 | US58_C0003G0028 | US58_C0001G0023 | RNA binding S1 domain protein. | Translation initiation factor IF-3; Belongs to the IF-3 family. | 0.570 |
KKQ41245.1 | efp | US58_C0003G0028 | US58_C0005G0065 | RNA binding S1 domain protein. | Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | 0.697 |
KKQ41245.1 | rplM | US58_C0003G0028 | US58_C0004G0003 | RNA binding S1 domain protein. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.999 |
KKQ41245.1 | rplQ | US58_C0003G0028 | US58_C0004G0002 | RNA binding S1 domain protein. | 50S ribosomal protein L17. | 0.999 |
KKQ41245.1 | rplT | US58_C0003G0028 | US58_C0001G0021 | RNA binding S1 domain protein. | 50S ribosomal subunit protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. | 0.999 |
KKQ41245.1 | rpmI | US58_C0003G0028 | US58_C0001G0022 | RNA binding S1 domain protein. | 50S ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family. | 0.940 |
KKQ41245.1 | rpsI | US58_C0003G0028 | US58_C0004G0004 | RNA binding S1 domain protein. | Ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family. | 0.999 |
KKQ41245.1 | rpsR | US58_C0003G0028 | US58_C0005G0067 | RNA binding S1 domain protein. | 30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. | 0.972 |
KKQ41245.1 | smpB | US58_C0003G0028 | US58_C0001G0024 | RNA binding S1 domain protein. | SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] | 0.420 |
KKQ41349.1 | KKQ41245.1 | US58_C0001G0023 | US58_C0003G0028 | Translation initiation factor IF-3; Belongs to the IF-3 family. | RNA binding S1 domain protein. | 0.570 |
KKQ41349.1 | efp | US58_C0001G0023 | US58_C0005G0065 | Translation initiation factor IF-3; Belongs to the IF-3 family. | Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | 0.499 |
KKQ41349.1 | rplM | US58_C0001G0023 | US58_C0004G0003 | Translation initiation factor IF-3; Belongs to the IF-3 family. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.999 |
KKQ41349.1 | rplQ | US58_C0001G0023 | US58_C0004G0002 | Translation initiation factor IF-3; Belongs to the IF-3 family. | 50S ribosomal protein L17. | 0.496 |
KKQ41349.1 | rplT | US58_C0001G0023 | US58_C0001G0021 | Translation initiation factor IF-3; Belongs to the IF-3 family. | 50S ribosomal subunit protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. | 0.999 |
KKQ41349.1 | rpmI | US58_C0001G0023 | US58_C0001G0022 | Translation initiation factor IF-3; Belongs to the IF-3 family. | 50S ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family. | 0.999 |
KKQ41349.1 | rpsI | US58_C0001G0023 | US58_C0004G0004 | Translation initiation factor IF-3; Belongs to the IF-3 family. | Ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family. | 0.947 |
KKQ41349.1 | rpsR | US58_C0001G0023 | US58_C0005G0067 | Translation initiation factor IF-3; Belongs to the IF-3 family. | 30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. | 0.974 |
KKQ41349.1 | smpB | US58_C0001G0023 | US58_C0001G0024 | Translation initiation factor IF-3; Belongs to the IF-3 family. | SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] | 0.419 |
def | rplM | US58_C0004G0014 | US58_C0004G0003 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.999 |
def | rplQ | US58_C0004G0014 | US58_C0004G0002 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 50S ribosomal protein L17. | 0.999 |