STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KKQ40044.1Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (496 aa)    
Predicted Functional Partners:
KKQ40562.1
Primase protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
  
 0.999
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
 
 
 
 0.948
dnaX
Polymerase III, subunit gamma and tau protein; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
   
 
 0.831
KKQ41126.1
Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
  
 
 0.828
KKQ40946.1
Polymerase III, delta prime subunit protein.
   
 
 0.822
KKQ39244.1
Hypothetical protein; Belongs to the helicase family. UvrD subfamily.
  
 
 0.816
KKQ39512.1
Elongation factor Tu.
   
   0.802
KKQ39280.1
Elongation factor Tu.
   
   0.802
KKQ41143.1
Single-stranded DNA-binding protein.
  
 
 0.729
KKQ40258.1
CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.
  
 
  0.726
Your Current Organism:
Magasanikbacteria bacterium GW2011GWA2378
NCBI taxonomy Id: 1619036
Other names: C. Magasanikbacteria bacterium GW2011_GWA2_37_8, Candidatus Magasanikbacteria bacterium GW2011_GWA2_37_8, Parcubacteria (Magasanikbacteria) bacterium GW2011_GWA2_37_8
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