STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KKQ49525.1Phosphomevalonate kinase. (315 aa)    
Predicted Functional Partners:
KKQ49526.1
Mevalonate diphosphate decarboxylase.
 
 
 0.998
KKQ49521.1
Hydroxymethylglutaryl-CoA reductase, degradative; Belongs to the HMG-CoA reductase family.
  
 0.926
KKQ49522.1
Hypothetical protein.
 
 
 0.857
KKQ48734.1
Isopentenyl-diphosphate Delta-isomerase.
  
 
 0.559
KKQ49524.1
Hypothetical protein.
       0.536
KKQ49527.1
Hypothetical protein.
       0.533
KKQ48963.1
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
   
 
 0.461
KKQ48883.1
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
   
 
 0.461
Your Current Organism:
candidate division TM6 bacterium GW2011GWF23810
NCBI taxonomy Id: 1619084
Other names: c. division TM6 bacterium GW2011_GWF2_38_10, candidate division TM6 bacterium GW2011_GWF2_38_10
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