STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCP98593.1AIPR protein. (583 aa)    
Predicted Functional Partners:
SCP98596.1
Z1 domain-containing protein.
 
 
 0.968
SCP98598.1
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
  
 0.965
SCP98594.1
Putative PD-(D/E)XK family member.
 
   
 0.963
SCP98592.1
DNA (cytosine-5)-methyltransferase 1.
 
   
 0.949
SCP94874.1
DNA gyrase subunit A.
  
 
 0.940
gyrA
DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
  
 
 0.940
SCP98589.1
DNA mismatch endonuclease, patch repair protein; May nick specific sequences that contain T:G mispairs resulting from m5C-deamination.
 
     0.841
SCP98599.1
Hypothetical protein.
       0.773
SCP98590.1
Uncharacterized conserved protein.
       0.737
recF
DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family.
  
  
 0.661
Your Current Organism:
Anaerobium acetethylicum
NCBI taxonomy Id: 1619234
Other names: A. acetethylicum, Anaerobium acetethylicum Patil et al. 2015, Clostridiales bacterium GluBS11, DSM 29698, KCTC 15450, LMG 28619, LMG:28619, strain GluBS11
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