node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARJ05102.1 | dcd | B5808_07710 | B5808_18685 | Nucleoside-diphosphate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | dCTP deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. | 0.924 |
ARJ05102.1 | dut | B5808_07710 | B5808_09675 | Nucleoside-diphosphate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.947 |
ARJ05102.1 | tmk | B5808_07710 | B5808_13190 | Nucleoside-diphosphate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.932 |
ARJ05399.1 | dut | B5808_09330 | B5808_09675 | Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.958 |
ARJ05459.1 | ARJ05460.1 | B5808_09660 | B5808_09665 | ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.800 |
ARJ05459.1 | ARJ05461.1 | B5808_09660 | B5808_09670 | ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.799 |
ARJ05459.1 | dut | B5808_09660 | B5808_09675 | ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.773 |
ARJ05460.1 | ARJ05459.1 | B5808_09665 | B5808_09660 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.800 |
ARJ05460.1 | ARJ05461.1 | B5808_09665 | B5808_09670 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.897 |
ARJ05460.1 | dut | B5808_09665 | B5808_09675 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.845 |
ARJ05461.1 | ARJ05459.1 | B5808_09670 | B5808_09660 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.799 |
ARJ05461.1 | ARJ05460.1 | B5808_09670 | B5808_09665 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.897 |
ARJ05461.1 | dut | B5808_09670 | B5808_09675 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.845 |
ARJ06080.1 | ARJ06394.1 | B5808_13260 | B5808_15110 | Thymidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.907 |
ARJ06080.1 | dut | B5808_13260 | B5808_09675 | Thymidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.971 |
ARJ06080.1 | thyA | B5808_13260 | B5808_04490 | Thymidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.964 |
ARJ06080.1 | tmk | B5808_13260 | B5808_13190 | Thymidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.932 |
ARJ06394.1 | ARJ06080.1 | B5808_15110 | B5808_13260 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thymidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.907 |
ARJ06394.1 | dut | B5808_15110 | B5808_09675 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.900 |
ARJ06394.1 | thyA | B5808_15110 | B5808_04490 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.911 |