STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARJ05474.12-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (489 aa)    
Predicted Functional Partners:
ARJ05473.1
Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.998
ARJ05760.1
MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.997
ARJ06718.1
MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.997
ARJ05234.1
Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.994
ARJ05624.1
2-oxoglutarate dehydrogenase E1 component; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
0.994
sucC
succinate--CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 0.981
sucD
succinate--CoA ligase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 0.977
ARJ05223.1
Pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.970
ARJ07058.1
Pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.970
ARJ07499.1
Alpha-ketoacid dehydrogenase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.959
Your Current Organism:
Cnuibacter physcomitrellae
NCBI taxonomy Id: 1619308
Other names: C. physcomitrellae, CGMCC 1.15041, Cnuibacter physcomitrellae Zhou et al. 2016, DSM 29843, Microbacteriaceae bacterium XA, strain XA
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