STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gcvHGlycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (125 aa)    
Predicted Functional Partners:
gcvP
Glycine dehydrogenase (aminomethyl-transferring); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
 
 0.999
ARJ07331.1
Glycine cleavage system protein T; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
ARJ05473.1
Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.980
ARJ05234.1
Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.975
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.974
B5808_01750
Hypothetical protein; Incomplete; partial on complete genome; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.907
ARJ05382.1
Glutamate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.887
ARJ05624.1
2-oxoglutarate dehydrogenase E1 component; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.882
ARJ07098.1
1-pyrroline-5-carboxylate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family.
    
 0.858
ARJ04054.1
1-pyrroline-5-carboxylate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family.
    
 0.858
Your Current Organism:
Cnuibacter physcomitrellae
NCBI taxonomy Id: 1619308
Other names: C. physcomitrellae, CGMCC 1.15041, Cnuibacter physcomitrellae Zhou et al. 2016, DSM 29843, Microbacteriaceae bacterium XA, strain XA
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