KJK11991.1 protein (Terrabacter sp. 28) - STRING interaction network

Nodes:

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second shell of interactors

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Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

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gene fusions

gene co-occurrence

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co-expression

protein homology

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[Homology]

Score

KJK11991.1

Sugar ABC transporter sugar-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (422 aa)

Predicted Functional Partners:

KJK11939.1

0.994

KJK11940.1

0.984

KJK11464.1

0.906

KJK12377.1

0.895

KJK11476.1

0.894

KJK11477.1

0.888

KJK11941.1

0.886

KJK12967.1

0.873

KJK11840.1

0.873

KJK12102.1

0.871

Your Current Organism:

Terrabacter sp. 28

NCBI taxonomy Id: 1619947
Other names: T. sp. 28

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KJK11464.1	KJK11476.1	UB45_13560	UB45_13670	Sugar ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.636
KJK11464.1	KJK11477.1	UB45_13560	UB45_13675	Sugar ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.956
KJK11464.1	KJK11840.1	UB45_13560	UB45_11415	Sugar ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Sugar ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.971
KJK11464.1	KJK11939.1	UB45_13560	UB45_12115	Sugar ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.816
KJK11464.1	KJK11940.1	UB45_13560	UB45_12120	Sugar ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Sugar ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.950
KJK11464.1	KJK11991.1	UB45_13560	UB45_12110	Sugar ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Sugar ABC transporter sugar-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.906
KJK11464.1	KJK12102.1	UB45_13560	UB45_10670	Sugar ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Sugar ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.765
KJK11464.1	KJK12377.1	UB45_13560	UB45_08965	Sugar ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.608
KJK11464.1	KJK12967.1	UB45_13560	UB45_06785	Sugar ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.920
KJK11476.1	KJK11464.1	UB45_13670	UB45_13560	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Sugar ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.636
KJK11476.1	KJK11477.1	UB45_13670	UB45_13675	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.987
KJK11476.1	KJK11840.1	UB45_13670	UB45_11415	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Sugar ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.971
KJK11476.1	KJK11939.1	UB45_13670	UB45_12115	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.732
KJK11476.1	KJK11940.1	UB45_13670	UB45_12120	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Sugar ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.950
KJK11476.1	KJK11991.1	UB45_13670	UB45_12110	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Sugar ABC transporter sugar-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.894
KJK11476.1	KJK12102.1	UB45_13670	UB45_10670	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Sugar ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.737
KJK11476.1	KJK12377.1	UB45_13670	UB45_08965	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.652
KJK11476.1	KJK12967.1	UB45_13670	UB45_06785	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.924
KJK11477.1	KJK11464.1	UB45_13675	UB45_13560	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Sugar ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.956
KJK11477.1	KJK11476.1	UB45_13675	UB45_13670	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.987

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Network Stats

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Functional enrichments in your networkNote: some enrichments may be expected here (why?)
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Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006707

Cholesterol catabolic process

3 of 11

2.4

1.75

0.00053

GO:0006629

Lipid metabolic process

6 of 437

1.11

0.99

0.00055

GO:0006633

Fatty acid biosynthetic process

3 of 103

1.43

0.77

0.0220

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0031177

Phosphopantetheine binding

3 of 29

1.98

1.22

0.0044

GO:0004315

3-oxoacyl-[acyl-carrier-protein] synthase activity

3 of 35

1.9

1.2

0.0044

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:9435

Mixed, incl. GMC oxidoreductase, and Oxygen oxidoreductase covalent FAD-binding site

3 of 6

2.67

2.04

0.00018

CL:2969

Mixed, incl. DUF35 OB-fold domain, acyl-CoA-associated, and Thiolase

3 of 10

2.44

1.89

0.00030

CL:3441

ACP-like superfamily, and MbtH-like domain

3 of 55

1.7

1.09

0.0057

CL:3450

This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group., and Male sterility protein

2 of 11

2.23

1.07

0.0103

CL:3430

Mixed, incl. ACP-like superfamily, and Cytochrome P450

4 of 163

1.36

0.96

0.0053

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

kphy00984

Steroid degradation

3 of 17

2.21

2.0

0.00014

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0034081

Polyketide synthase complex

3 of 28

2.0

1.46

0.0014

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0001

2Fe-2S

2 of 9

2.31

1.14

0.0076

KW-0596

Phosphopantetheine

3 of 59

1.67

1.03

0.0076

KW-0408

Iron

3 of 160

1.24

0.6

0.0449

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00975

Thioesterase domain

3 of 9

2.49

1.98

0.00021

PF05199

GMC oxidoreductase

2 of 9

2.31

0.83

0.0295

PF00111

2Fe-2S iron-sulfur cluster binding domain

2 of 11

2.23

0.83

0.0295

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR001031

Thioesterase

3 of 12

2.37

1.61

0.0010

IPR006162

Phosphopantetheine attachment site

3 of 29

1.98

1.17

0.0056

IPR020806

Polyketide synthase, phosphopantetheine-binding domain

3 of 35

1.9

1.12

0.0064

IPR007867

Glucose-methanol-choline oxidoreductase, C-terminal

2 of 9

2.31

0.88

0.0239

IPR000172

Glucose-methanol-choline oxidoreductase, N-terminal

2 of 9

2.31

0.88

0.0239

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00823

Phosphopantetheine attachment site

3 of 20

2.14

1.81

0.00031

SM00826

PKS_DH

2 of 11

2.23

1.13

0.0078

SM00825

Beta-ketoacyl synthase

2 of 12

2.19

1.13

0.0078

SM00822

This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group.

2 of 14

2.12

1.12

0.0078

SM00827

Acyl transferase domain in polyketide synthase (PKS) enzymes.

2 of 15

2.09

1.11

0.0078

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