Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
aepYPhosphonopyruvate decarboxylase. (378 aa)    
Predicted Functional Partners:
CEM60428.1
2-aminoethylphosphonate--pyruvate transaminase.
 
 
 0.998
aepX
Phosphoenolpyruvate mutase.
 
 0.998
crt
3-hydroxybutyryl-CoA dehydratase; Belongs to the enoyl-CoA hydratase/isomerase family.
   
 0.837
ydbK
Putative 2-oxoacid-flavodoxin fused oxidoreductase:conserved protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
  
 0.817
nifJ
Pyruvate-flavodoxin oxidoreductase.
  
  
 0.813
CEM63305.1
Dehydrogenase, FMN-dependent.
  
 
 0.734
ilvA
Threonine ammonia-lyase.
  
 
 0.706
CEM61264.1
Hydrolase, NUDIX family.
   
 
  0.704
CEM61966.1
Rubredoxin.
  
 0.614
CEM60427.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
     
 0.608
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
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