Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
CEM60672.1Diguanylate cyclase (GGDEF) domain protein. (452 aa)    
Predicted Functional Partners:
CEM61310.1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein (modular protein).
  
  
 0.813
CEM60673.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
       0.793
CEM60674.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
       0.793
CEM60676.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
       0.790
CEM60675.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
       0.773
CEM61784.1
Diguanylate cyclase (GGDEF) domain protein (fragment).
  
 
 0.758
CEM61785.1
Diguanylate cyclase (GGDEF) domain protein (fragment).
  
  
 0.702
CEM61007.1
Response regulator receiver domain protein.
  
 
 0.647
CEM60678.1
Septum formation initiator.
       0.539
CEM60679.1
Putative Sua5/YciO/YrdC/YwlC family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the SUA5 family.
       0.529
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
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