STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yeiNConserved hypothetical protein; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family. (307 aa)    
Predicted Functional Partners:
CEM60804.1
Kinase, PfkB family.
 
 0.998
upp
Putative uracil phosphoribosyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
    
  0.908
udp
Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family.
    
  0.902
deoD
Purine nucleoside phosphorylase DeoD-type.
     
  0.900
apeB
Putative M18 family aminopeptidase 2; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
      0.872
CEM60802.1
Hypothetical protein; No homology to any previously reported sequences.
       0.581
CEM60801.1
Fibronectin type III domain protein.
       0.559
atpA-2
V-type ATP synthase alpha chain 2; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family.
 
      0.491
CEM60805.1
Hypothetical protein; No homology to any previously reported sequences.
       0.462
CEM60800.1
Conserved exported hypothetical protein; Homologs of previously reported genes of unknown function.
       0.414
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.