| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| atoB | clpP | TPHV1_240015 | TPHV1_120046 | acetyl-CoA acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; carrier; Belongs to the thiolase-like superfamily. Thiolase family. | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.676 |
| atoB | clpX | TPHV1_240015 | TPHV1_120047 | acetyl-CoA acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; carrier; Belongs to the thiolase-like superfamily. Thiolase family. | ATPase and specificity subunit of ClpX-ClpP ATP-dependent serine protease; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.664 |
| atoB | gctB | TPHV1_240015 | TPHV1_170008 | acetyl-CoA acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; carrier; Belongs to the thiolase-like superfamily. Thiolase family. | Glutaconate CoA-transferase subunit B. | 0.851 |
| atoB | lon | TPHV1_240015 | TPHV1_20056 | acetyl-CoA acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; carrier; Belongs to the thiolase-like superfamily. Thiolase family. | Lon protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.689 |
| atoB | nifJ | TPHV1_240015 | TPHV1_50039 | acetyl-CoA acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; carrier; Belongs to the thiolase-like superfamily. Thiolase family. | Pyruvate-flavodoxin oxidoreductase. | 0.969 |
| clpA | clpP | TPHV1_10054 | TPHV1_120046 | ATPase and specificity subunit of ClpA-ClpP ATP-dependent serine protease, chaperone activity; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.845 |
| clpA | clpX | TPHV1_10054 | TPHV1_120047 | ATPase and specificity subunit of ClpA-ClpP ATP-dependent serine protease, chaperone activity; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the ClpA/ClpB family. | ATPase and specificity subunit of ClpX-ClpP ATP-dependent serine protease; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.491 |
| clpA | lon | TPHV1_10054 | TPHV1_20056 | ATPase and specificity subunit of ClpA-ClpP ATP-dependent serine protease, chaperone activity; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the ClpA/ClpB family. | Lon protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.733 |
| clpB | clpP | TPHV1_40153 | TPHV1_120046 | Protein disaggregation chaperone; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.804 |
| clpB | lon | TPHV1_40153 | TPHV1_20056 | Protein disaggregation chaperone; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Lon protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.733 |
| clpP | atoB | TPHV1_120046 | TPHV1_240015 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | acetyl-CoA acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; carrier; Belongs to the thiolase-like superfamily. Thiolase family. | 0.676 |
| clpP | clpA | TPHV1_120046 | TPHV1_10054 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | ATPase and specificity subunit of ClpA-ClpP ATP-dependent serine protease, chaperone activity; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the ClpA/ClpB family. | 0.845 |
| clpP | clpB | TPHV1_120046 | TPHV1_40153 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Protein disaggregation chaperone; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.804 |
| clpP | clpX | TPHV1_120046 | TPHV1_120047 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | ATPase and specificity subunit of ClpX-ClpP ATP-dependent serine protease; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.998 |
| clpP | gctB | TPHV1_120046 | TPHV1_170008 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Glutaconate CoA-transferase subunit B. | 0.722 |
| clpP | lon | TPHV1_120046 | TPHV1_20056 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Lon protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.719 |
| clpP | nifJ | TPHV1_120046 | TPHV1_50039 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Pyruvate-flavodoxin oxidoreductase. | 0.695 |
| clpP | prs | TPHV1_120046 | TPHV1_200018 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Ribose-phosphate diphosphokinase; Belongs to the ribose-phosphate pyrophosphokinase family. | 0.696 |
| clpP | tig | TPHV1_120046 | TPHV1_120045 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. | 0.915 |
| clpP | tlyB | TPHV1_120046 | TPHV1_250012 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Hemolysin B; Belongs to the ClpA/ClpB family. | 0.806 |
